IN SILICO COMPARISON OF SEPARATE OR COMBINATORIAL EFFECTS OF PO-TENTIAL INHIBITORS OF THE SARS-COV-2 BINDING SITE OF ACE2

In Silico Comparison of Separate or Combinatorial Effects of Po-tential Inhibitors of the SARS-CoV-2 Binding Site of ACE2

Background: The COVID-19 is a pandemic viral infection with a high morbidity rate, leading to many worldwide deaths since the end of 2019.The RBD (Receptor Binding Domain) of SARS-CoV-2 through its spike utilizes several host molecules to enter host cells.One of the most important ones is the angiotensin-converting enzyme 2 (ACE2), an enzyme normal

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FUT2 promotes colorectal cancer metastasis by reprogramming fatty acid metabolism via YAP/TAZ signaling and SREBP-1

Abstract Colorectal cancer (CRC) ranks as the second most lethal cancer worldwide because of its high rate of metastasis, and approximately 20% of CRC patients have metastases at initial diagnosis.Metabolic reprogramming, a hallmark of cancer cells, has been implicated in the process of metastasis.We previously demonstrated that fucosyltransferase

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Pulmonary Anthracosis in A Lion Tailed Macaque (Macaca silenus), An Endangered Primate Species - A Case Report

Anthracosis is the blackish pigmentation of the lung parenchyma and tracheobronchial tree.A female Lion Tailed Bosch PIM851F17E 80cm 5 Zone Induction Hob Macaque aged 19 years was being kept captive in Thiruvananthapuram Zoo for 17 years.On 30th November 2019, the animal was found dead in the zoo and was subjected to a necropsy at the zoo hospital.

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